Biodefense Barrier Cream
Description
Reinforce the skin barrier
Ingredients:
AQSTEM ATACAMA, STEMCEM QUILLAY
Ingredients
AQSTEM ATACAMA
Stem cell tech for an impossibly rare desert flower
Cobiosa
Technical Information
INCI Name
Cistanthe Grandiflora Callus Extract; Glycerin; Pentylene Glycol
Recommended use level
1%-2%
Product Characteristics
Liquid
ISO Natural
50
ISO NOI
100
Benefits
- •Boosts Aquaporin-3 (AQP3) expression to enhance skin’s natural hydration pathways
- •Delivers visible hydration from 2 hours after application (in vivo tested)
- •Helps reduce inflammatory markers linked to redness and itching
- •Protects against oxidative stress and environmental damage
- •Sustainable stem cell technology with 100% natural origin content
Why AQSTEM ATACAMA?
Born in one of the harshest environments on earth, AQSTEM ATACAMA harnesses the extraordinary resilience of Cistanthe grandiflora — the iconic flower of Chile’s Atacama Desert. This ephemeral plant survives extreme drought and intense solar radiation, blooming only when conditions allow - once every 5 to 10 years!
Through advanced stem cell culture technology, Cobiosa has captured its adaptive survival mechanisms without harvesting the wild plant, preserving biodiversity while ensuring consistent efficacy .
At the heart of AQSTEM ATACAMA is its Smart Hydration System. The extract stimulates the expression of Aquaporin-3 (AQP3) — the key epidermal water and glycerol channel responsible for maintaining moisture balance. In vitro studies show a 2.3-fold increase in AQP3 gene expression after 24 hours, while ex vivo testing demonstrates a +66.8% increase in AQP3 protein synthesis .
In vivo results confirm rapid performance, with measurable hydration improvements from just 2 hours after a single application compared to placebo .
Beyond hydration, AQSTEM ATACAMA helps modulate inflammatory mediators such as IL-13 and IL-31, supporting skin comfort and barrier resilience .
The result? Skin that feels replenished, balanced and visibly revived — like the desert in bloom.
Through advanced stem cell culture technology, Cobiosa has captured its adaptive survival mechanisms without harvesting the wild plant, preserving biodiversity while ensuring consistent efficacy .
At the heart of AQSTEM ATACAMA is its Smart Hydration System. The extract stimulates the expression of Aquaporin-3 (AQP3) — the key epidermal water and glycerol channel responsible for maintaining moisture balance. In vitro studies show a 2.3-fold increase in AQP3 gene expression after 24 hours, while ex vivo testing demonstrates a +66.8% increase in AQP3 protein synthesis .
In vivo results confirm rapid performance, with measurable hydration improvements from just 2 hours after a single application compared to placebo .
Beyond hydration, AQSTEM ATACAMA helps modulate inflammatory mediators such as IL-13 and IL-31, supporting skin comfort and barrier resilience .
The result? Skin that feels replenished, balanced and visibly revived — like the desert in bloom.
Certification icons
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Cruelty Free
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Non-GMO
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Vegan