Ingredients
MAKISTEM
The maqui stem cell active for visibly brighter, more even-toned skin
Cobiosa
Technical Information
INCI Name
Glycerin, Aqua, Aristotelia Chilensis Callus Extract
Recommended use level
0.5%-1%
Product Characteristics
Liquid
Solubility
Water
ISO Natural
20
ISO NOI
100
Benefits
- •Helps visibly reduce all types of dark spots
- •Including UV-induced pigmentation
- •Supports collagen production for firmer
- •Smoother-looking skin
- •Protects against photoageing with powerful antioxidant activity
- •Promotes a more radiant
- •Even complexion over time
Why MAKISTEM?
MAKISTEM is a cutting-edge plant stem cell active derived from Aristotelia chilensis (maqui), a berry renowned for its exceptionally high polyphenol content. Developed through advanced biotechnological cell culture, this ingredient offers a sustainable yet highly potent approach to tackling uneven skin tone and early signs of ageing .
At the heart of its efficacy is its ability to intervene in melanin production while simultaneously supporting the skin’s structural integrity. In vitro studies show that MAKISTEM can reduce melanin synthesis by up to 40%, helping to visibly diminish hyperpigmentation at its source . At the same time, it boosts type I pro-collagen production, reinforcing the skin’s matrix for a firmer, more resilient appearance.
In vivo results further bring this to life: after 28 days, visible improvements were observed across multiple types of pigmentation—including superficial, brown, and UV-induced spots—with reductions noted in up to 86% of volunteers depending on spot type . This multi-pathway action makes it particularly compelling for formulations targeting radiance, photoageing, and uneven tone.
Lightweight and water-soluble, MAKISTEM integrates seamlessly into modern formulations, offering a sophisticated balance of brightening performance and skin longevity support—ideal for next-generation glow and anti-ageing concepts.
At the heart of its efficacy is its ability to intervene in melanin production while simultaneously supporting the skin’s structural integrity. In vitro studies show that MAKISTEM can reduce melanin synthesis by up to 40%, helping to visibly diminish hyperpigmentation at its source . At the same time, it boosts type I pro-collagen production, reinforcing the skin’s matrix for a firmer, more resilient appearance.
In vivo results further bring this to life: after 28 days, visible improvements were observed across multiple types of pigmentation—including superficial, brown, and UV-induced spots—with reductions noted in up to 86% of volunteers depending on spot type . This multi-pathway action makes it particularly compelling for formulations targeting radiance, photoageing, and uneven tone.
Lightweight and water-soluble, MAKISTEM integrates seamlessly into modern formulations, offering a sophisticated balance of brightening performance and skin longevity support—ideal for next-generation glow and anti-ageing concepts.
Certification icons
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Vegan
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Cruelty Free
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Non-GMO